COMBINATION OF ANTI-CTLA4 ANTIBODY WITH DIVERSE THERAPEUTIC REGIMENS FOR THE SYNERGISTIC TREATMENT OF PROLIFERATIVE DISEASES - Patent 2456790

(19)

(11)

EP 2 456 790 A1

(12)

(43)	Date of publication:
	30.05.2012 Bulletin 2012/22

(21)	Application number: 09749268.0

(22)	Date of filing: 29.10.2009

(51)

International Patent Classification (IPC):

C07K 16/28^(2006.01)
A61K 31/385^(2006.01)
A61K 33/24^(2006.01)
A61P 35/00^(2006.01)
A61K 39/395^(2006.01)

C07K 16/18^(2006.01)
A61K 31/337^(2006.01)
A61K 31/506^(2006.01)
A61K 45/06^(2006.01)

(86)	International application number:
	PCT/US2009/062519

(87)	International publication number:
	WO 2011/011027 (27.01.2011 Gazette 2011/04)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30)

Priority:

20.07.2009 US 226910 P
30.07.2009 US 462168
30.07.2009 WO PCT/US2009/005220

(71)	Applicant: Bristol-Myers Squibb Company
	Princeton, NJ 05843-4000 (US)

(72)	Inventors:
	LEE, Francis, Y. Princeton, New Jersey 08543 (US) JURE-KUNKEL, Maria Princeton, New Jersey 08543 (US)

(74)	Representative: Reitstötter - Kinzebach
	Patentanwälte Sternwartstrasse 4 81679 München 81679 München (DE)

(54)	COMBINATION OF ANTI-CTLA4 ANTIBODY WITH DIVERSE THERAPEUTIC REGIMENS FOR THE SYNERGISTIC TREATMENT OF PROLIFERATIVE DISEASES