(19)
(11) EP 2 459 533 A1

(12)

(43) Date of publication:
06.06.2012 Bulletin 2012/23

(21) Application number: 10804801.8

(22) Date of filing: 30.07.2010
(51) International Patent Classification (IPC): 
C07D 209/14(2006.01)
A61K 31/4045(2006.01)
C07D 209/24(2006.01)
A61P 35/00(2006.01)
(86) International application number:
PCT/SG2010/000286
(87) International publication number:
WO 2011/014128 (03.02.2011 Gazette 2011/05)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30) Priority: 30.07.2009 SG 200905128
20.11.2009 SG 200907728

(71) Applicant: National University of Singapore
Singapore 119260 (SG)

(72) Inventors:
  • LEOW, Jo Lene
    Singapore 117543 (SG)
  • CASEY, Mei-Wang
    Singapore 169857 (SG)
  • CASEY, Patrick J
    Singapore 169857 (SG)
  • GO, Mei Lin
    Singapore 117543 (SG)
  • SURESH, Kumar Gorla
    Massachusetts 02454 (US)

(74) Representative: Viering, Jentschura & Partner 
Kennedydamm 55/Roßstr.
40476 Düsseldorf
40476 Düsseldorf (DE)

   


(54) SMALL MOLECULE INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE WITH POTENTIAL ANTICANCER ACTIVITY