BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS

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EP 2 461 683 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	03.06.2015 Bulletin 2015/23

(45)	Mention of the grant of the patent:
	29.04.2015 Bulletin 2015/18

(21)	Application number: 10807186.1

(22)	Date of filing: 05.08.2010

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International Patent Classification (IPC):

C07C 229/48^(2006.01)
C07C 237/52^(2006.01)
C07C 311/51^(2006.01)
C07D 207/16^(2006.01)
C07D 211/60^(2006.01)
C07D 215/20^(2006.01)
C07D 257/04^(2006.01)
C07D 403/06^(2006.01)
A61P 3/10^(2006.01)
A61P 35/00^(2006.01)

C07C 237/08^(2006.01)
C07C 309/14^(2006.01)
C07D 205/04^(2006.01)
C07D 209/08^(2006.01)
C07D 211/62^(2006.01)
C07D 217/24^(2006.01)
C07D 305/08^(2006.01)
C07D 417/06^(2006.01)
A61P 29/00^(2006.01)
A61P 11/06^(2006.01)

(86)	International application number:
	PCT/US2010/044607

(87)	International publication number:
	WO 2011/017561 (10.02.2011 Gazette 2011/06)

(54)	BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS BIZYKLISCHE ARYL-SPHINGOSIN-1-PHOSPHAT-ANALOGE ANALOGUES D'ARYLSPHINGOSINE-1-PHOSPHATE BICYCLIQUES

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
	Designated Extension States:
	BA ME RS

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Priority:

05.08.2009 US 231539 P

(43)	Date of publication of application:
	13.06.2012 Bulletin 2012/24

(60)	Divisional application:
	15165518.0

(73)	Proprietor: Biogen MA Inc.
	Cambridge, MA 02142 (US)

(72)	Inventors:
	THOMAS, Jermaine Chelsea MA 02150 (US) LIU, Xiaogao Dover MA 02030 (US) LIN, Edward, Yin-Shiang Chestnut Hill MA 02467 (US) ZHENG, Guo, Zhu Lexington MA 02420 (US) MA, Bin Arlington MA 02474 (US) CALDWELL, Richard, D. Somerville MA 02144 (US) GUCKIAN, Kevin, M. Marlborough MA 01752 (US) KUMARAVEL, Gnanasambandam Westford MA 01886 (US) TAVERAS, Arthur, G. Southborough MA 01772 (US)

(74)	Representative: Miller, David James et al
	Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)

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References cited: :

WO-A1-2006/080477
WO-A1-2009/023854
WO-A1-2010/051031
US-A1- 2008 027 036

WO-A1-2007/092638
WO-A1-2010/051030
US-A1- 2004 254 215
US-A1- 2009 131 400

CHRISTINA N. CARRIGAN ET AL: "Synthesis and in Vitro Pharmacology of Substituted Quinoline-2,4-dicarboxylic Acids as Inhibitors of Vesicular Glutamate Transport", JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, no. 11, 1 May 2002 (2002-05-01), pages 2260-2276, XP55040588, ISSN: 0022-2623, DOI: 10.1021/jm010261z


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).