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<SDOBI lang="en"><B000><eptags><B001EP>ATBECHDEDKESFR..GRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNO....SM..................</B001EP><B003EP>*</B003EP><B005EP>J</B005EP><B007EP>DIM360 Ver 2.41 (21 Oct 2013) -  2999001/0</B007EP><B070EP>The file contains technical information submitted after the application was filed and not included in this specification</B070EP></eptags></B000><B100><B110>2467724</B110><B120><B121>CORRECTED EUROPEAN PATENT SPECIFICATION</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20141029</date></B140><B150><B151>W1</B151><B153>84</B153><B155><B1551>de</B1551><B1552>Bibliographie</B1552><B1551>en</B1551><B1552>Bibliography</B1552><B1551>fr</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>10747657.4</B210><B220><date>20100819</date></B220><B240><B241><date>20120315</date></B241><B242><date>20130307</date></B242></B240><B250>en</B250><B251EP>en</B251EP><B260>en</B260></B200><B300><B310>0914535</B310><B320><date>20090819</date></B320><B330><ctry>GB</ctry></B330><B310>201001079</B310><B320><date>20100122</date></B320><B330><ctry>GB</ctry></B330></B300><B400><B405><date>20141029</date><bnum>201444</bnum></B405><B430><date>20120627</date><bnum>201226</bnum></B430><B450><date>20140723</date><bnum>201430</bnum></B450><B452EP><date>20140206</date></B452EP><B480><date>20141029</date><bnum>201444</bnum></B480></B400><B500><B510EP><classification-ipcr sequence="1"><text>G01N  33/68        20060101AFI20110307BHEP        </text></classification-ipcr></B510EP><B540><B541>de</B541><B542>ÜBERLEBENSPROGNOSETEST</B542><B541>en</B541><B542>SURVIVAL PROGNOSTIC ASSAY</B542><B541>fr</B541><B542>DOSAGE PRONOSTIQUE DE DÉTERMINATION DE LA SURVIE</B542></B540><B560><B561><text>EP-A1- 0 044 219</text></B561><B561><text>EP-A1- 0 336 472</text></B561><B561><text>WO-A1-2005/103717</text></B561><B561><text>WO-A1-2006/079816</text></B561><B561><text>WO-A1-2007/125338</text></B561><B561><text>WO-A2-2010/049672</text></B561><B561><text>DE-U1-202004 012 479</text></B561><B561><text>GB-B- 2 472 518</text></B561><B562><text>LE BRICON THIERRY ET AL: "Urinary free light chain analysis by the Freelite(R) immunoassay: A preliminary study in multiple myeloma" CLINICAL BIOCHEMISTRY, ELSEVIER INC, US, CA, vol. 35, no. 7, 1 October 2002 (2002-10-01), pages 565-567, XP008127742 ISSN: 0009-9120</text></B562><B562><text>RAJKUMAR S VINCENT ET AL: "Presence of monoclonal free light chains in serum predicts risk of progression in monoclonal gammopathy of undetermined significance (MGUS)" BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 102, no. 11, 16 November 2003 (2003-11-16), page 935A, XP008127772 ISSN: 0006-4971</text></B562><B562><text>STAGGS BRENT ET AL: "Comparison of serum quantitative free light chains (Freelite) to serum quantitative total light chains in recurrent multiple myeloma" ARCHIVES OF PATHOLOGY &amp; LABORATORY MEDICINE, COLLEGE OF AMERICAN PATHOLOGISTS, US, vol. 128, no. 2, 1 February 2004 (2004-02-01), page 143, XP008127760 ISSN: 0363-0153</text></B562><B562><text>SHOWELL P J ET AL: "Correlation of FREELITE (TM) and cystatin C in chronic kidney disease on the binding site SPAPLUS (TM) bench-top analyser" CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 53, no. 6 sup.S, 1 June 2007 (2007-06-01), page A129, XP008127771 ISSN: 0009-9147</text></B562><B562><text>HUTCHISON COLIN A ET AL: "Quantitative assessment of serum and urinary polyclonal free light chains in patients with type II diabetes: an early marker of diabetic kidney disease?" EXPERT OPINION ON THERAPEUTIC TARGETS JUN 2008 LNKD- PUBMED:18479214, vol. 12, no. 6, June 2008 (2008-06), pages 667-676, XP8132516 ISSN: 1744-7631</text></B562><B562><text>HOFMANN W ET AL: "A new concept for detection of Bence Jones proteinuria in patients with monoclonal gammopathy" CLINICAL LABORATORY, CLIN LAB PUBLICATIONS, HEIDELBERG, vol. 50, no. 3-4, 1 January 2004 (2004-01-01), pages 181-185, XP008132515 ISSN: 1433-6510</text></B562><B562><text>KYRTSONIS MARIE-CHRISTINE ET AL: "Serum free light chain ratio (FLCR) at diagnosis constitute a powerful prognostic factor of survival in multiple myeloma (MM)" BLOOD; 48TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ORLANDO,FL, USA; DECEMBER 09 -12, 2006, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 108, no. 11 part 1, 16 November 2006 (2006-11-16), pages 1-3, XP008132501 ISSN: 0006-4971</text></B562><B562><text>ROSSI JEAN-FRANCOIS ET AL: "A phase I/II study of atacicept (TACI-Ig) to neutralize APRIL and BLyS in patients with refractory or relapsed multiple myeloma (MM) or active previously treated waldenstrom's macroglobulinemia (WM)" BLOOD; 48TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ORLANDO,FL, USA; DECEMBER 09 -12, 2006, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 108, no. 11 part 1, 16 November 2006 (2006-11-16), pages 1-3, XP008132499 ISSN: 0006-4971</text></B562><B562><text>KATZMANN JERRY A ET AL: "Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: Relative sensitivity for detection of monoclonal light chains" CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 48, no. 9, 1 September 2002 (2002-09-01), pages 1437-1444, XP002378160 ISSN: 0009-9147</text></B562><B562><text>ABADIE JUDE M ET AL: "Are Renal Reference Intervals Required When Screening for Plasma Cell Disorders With Serum Free Light Chains and Serum Protein Electrophoresis?" 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ET AL.: "Serum Free Light Chains in Plasmacell Dyscrasias: Comparison of 2 assays", XI INTERNATIONAL MYELOMA CONFERENCE, 25 June 2007 (2007-06-25), - 30 June 2007 (2007-06-30),</text></B562><B562><text>ANONYMOUS: 'Freelite TM', [Online] Retrieved from the Internet: &lt;URL:http://www.bindingsite.com/freelite&gt; [retrieved on 2011-03-10]</text></B562><B562><text>RAJKUMAR S VINCENT ET AL: "Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance", BLOOD, vol. 106, no. 3, August 2005 (2005-08), pages 812-817,803, ISSN: 0006-4971</text></B562></B560></B500><B600><B620EP><parent><cdoc><dnum><anum>14171848.6</anum></dnum><date>20140610</date></cdoc></parent></B620EP></B600><B700><B720><B721><snm>MEAD, Graham Peter</snm><adr><str>P O Box 11712</str><city>Birmingham B14 4ZB</city><ctry>GB</ctry></adr></B721><B721><snm>BRADWELL, Arthur Randall</snm><adr><str>P O Box 11712</str><city>Birmingham B14 4ZB</city><ctry>GB</ctry></adr></B721></B720><B730><B731><snm>The Binding Site Group Limited</snm><iid>101134183</iid><irf>P333719EP-PCT</irf><adr><str>PO Box 11712</str><city>Birmingham
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