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EP 2 470 650 A1

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(43) Date of publication: 04.07.2012 Bulletin 2012/27 (21) Application number: 10811487.7 (22) Date of filing: 23.08.2010

(51) International Patent Classification (IPC):  C12N 15/09(2006.01) A61K 48/00(2006.01) C07K 7/06(2006.01) A61K 31/7105(2006.01) A61P 35/00(2006.01) C07K 14/00(2006.01) (86) International application number: PCT/JP2010/005169 (87) International publication number: WO 2011/024428 (03.03.2011 Gazette 2011/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 24.08.2009 US 275047 P (71) Applicant: Oncotherapy Science, Inc. Kawasaki-shi Kanagawa 213-0012 (JP)	(72) Inventors: NAKAMURA, Yusuke Tokyo 113-8654 (JP) KATAGIRI, Toyomasa Tokyo 113-8654 (JP) TSUNODA, Takuya Kawasaki-shi Kanagawa 213-0012 (JP) (74) Representative: Plougmann & Vingtoft A/S  Rued Langgaards Vej 8 2300 Copenhagen S 2300 Copenhagen S (DK)