(19)

(11)

EP 2 473 506 A2

(12)

(88) Date of publication A3: 21.07.2011 (43) Date of publication: 11.07.2012 Bulletin 2012/28 (21) Application number: 10814469.2 (22) Date of filing: 02.09.2010

(51) International Patent Classification (IPC):  C07D 413/12(2006.01) A61K 31/5377(2006.01) C07D 211/76(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2010/047615 (87) International publication number: WO 2011/028860 (10.03.2011 Gazette 2011/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 02.09.2009 US 275754 P (71) Applicant: Canthera Therapeutics, Inc. Boston, MA 02210 (US)	(72) Inventors: FOLEY, Michael, Andrew Chestnut Hill, MA 02467 (US) GOULD, Robert Beverly, MA 01915 (US) ELLIOT, Peter Marlboro, MA 01752 (US) MANDINOVA, Anna Newton, MA 02460 (US) LEE, Sam Newton, MA 02459 (US) (74) Representative: Knuth-Lehtola, Sisko Hillevi  Berggren Oy Ab P.O. Box 16 00101 Helsinki 00101 Helsinki (FI)