NOVEL PROTECTING GROUP FOR SYNTHESIZING RNA AND DERIVATIVE THEREOF

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EP 2 479 182 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	13.07.2016 Bulletin 2016/28

(45)	Mention of the grant of the patent:
	25.05.2016 Bulletin 2016/21

(21)	Application number: 10817185.1

(22)	Date of filing: 15.09.2010

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International Patent Classification (IPC):

C07H 19/067^(2006.01)
C07F 9/6558^(2006.01)
C07F 9/6584^(2006.01)
C07H 19/167^(2006.01)
C07H 21/02^(2006.01)

C07F 7/18^(2006.01)
C07F 9/6561^(2006.01)
C07H 19/10^(2006.01)
C07H 19/20^(2006.01)
C07C 43/13^(2006.01)

(86)	International application number:
	PCT/JP2010/065900

(87)	International publication number:
	WO 2011/034072 (24.03.2011 Gazette 2011/12)

(54)	NOVEL PROTECTING GROUP FOR SYNTHESIZING RNA AND DERIVATIVE THEREOF NEUE SCHUTZGRUPPE FÜR SYNTHESE VON RNA UND DERIVAT DARAUS NOUVEAU GROUPE PROTECTEUR POUR SYNTHÉTISER DE L'ARN ET DÉRIVÉ DE CELUI-CI

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

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Priority:

16.09.2009 US 242877 P

(43)	Date of publication of application:
	25.07.2012 Bulletin 2012/30

(73)	Proprietor: Wave Life Sciences Japan, Inc.
	Kagoshima-shi Kagoshima 891-1394 (JP)

(72)	Inventors:
	WADA Takeshi Kashiwa-shi Chiba 277-0852 (JP) SHIMIZU Mamoru Kashiwa-shi Chiba 277-0885 (JP)

(74)	Representative: Godemeyer Blum Lenze Patentanwälte Partnerschaft mbB - werkpatent
	An den Gärten 7 51491 Overath 51491 Overath (DE)

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References cited: :

EP-A1- 1 795 536
WO-A1-2005/023828
WO-A1-2006/022323
DD-A1- 133 885

WO-A1-2004/085494
WO-A1-2005/092909
WO-A1-2007/064291
US-A- 4 542 142

ZHANG ET AL: "Asymmetric synthesis of novel alpha-amino acids with beta-branched side chains", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 17, no. 9, 3 April 2007 (2007-04-03), pages 2401-2403, XP022015312, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2007.02.041
KIM S-G ET AL: "Use of the hexafluoro-2-butyl protecting group in the synthesis of DNA fragments via the phosphoramidite approach on solid supports", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 5, no. 15, 3 August 1995 (1995-08-03) , pages 1663-1666, XP004135404, ISSN: 0960-894X, DOI: 10.1016/0960-894X(95)00269-Y
Kenji Uneyama ET AL: "BISTRIFLUOROMETHYLATION OF ACRYLAMIDE FOR TRIFLUOROMETHYLATED SYNTHETIC BLOCKS", Tetrahedron Letters,, vol. 30, no. 1, 1 January 1989 (1989-01-01), pages 109-110, XP055108110,

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