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EP 2 480 261 A2

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(88) Date of publication A3: 23.06.2011 (43) Date of publication: 01.08.2012 Bulletin 2012/31 (21) Application number: 10754440.5 (22) Date of filing: 17.08.2010

(51) International Patent Classification (IPC):  A61L 17/00(2006.01) (86) International application number: PCT/EP2010/061994 (87) International publication number: WO 2011/035989 (31.03.2011 Gazette 2011/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 24.09.2009 RU 2009135435 (71) Applicants: Closed Stock Company "Institute Of Applied Nanotechnology" Moscow 124482 (RU) Fondazione Salvatore Maugeri - Clinica del Lavoro e della Riabilitazione 27100 Pavia (IT) SIB Laboratories Limited Valletta, VLT 1362 (MT)

(72) Inventors: BARBAKOV, Vladimir, Ilych Moscow 124460 (RU) BEKLEMYSHEV, Viacheslav, Ivanovich Moscow 124460 (RU) BEKLEMYSHEVA, Evgeniya, Fedorovna Moscow 124460 (RU) MAKHONIN, Igor, Ivanovich Mendeleevo 141570 (RU) MAUGERI, Umberto, Orazio, Giuseppe I-27040 Calvignano (IT) MESHKOVA, Irina, Mihailovna Mendeleevo 141570 (RU) SOLODOVNIKOV, Vladimir, Aleksandrovich Moscow 119313 (RU) (74) Representative: Gervasi, Gemma et al Notarbartolo & Gervasi S.p.A. Corso di Porta Vittoria 9 20122 Milano 20122 Milano (IT)