(19)

(11)

EP 2 486 132 A1

(12)

(43) Date of publication: 15.08.2012 Bulletin 2012/33 (21) Application number: 10704873.8 (22) Date of filing: 10.02.2010

(51) International Patent Classification (IPC):  C12N 15/10(2006.01) C07K 14/47(2006.01) (86) International application number: PCT/US2010/023803 (87) International publication number: WO 2011/043834 (14.04.2011 Gazette 2011/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (30) Priority: 09.10.2009 US 577067 09.10.2009 WO PCT/US2009/060271 (71) Applicant: Anaphore, Inc. La Jolla, CA 92037 (US)	(72) Inventors: WILD, Martha San Diego CA 92104 (US) KRETZ-ROMMEL, Anke San Diego CA 92116 (US) BOWDISH, Katherine Del Mar CA 92014 (US) RENSHAW, Mark San Diego CA 92129 (US) (74) Representative: Williams, Richard Andrew Norman  Harrison Goddard Foote 8th Floor 140 London Wall London EC2Y 5DN London EC2Y 5DN (GB)