(19)

(11)

EP 2 493 918 A2

(12)

(88) Date of publication A3: 25.08.2011 (43) Date of publication: 05.09.2012 Bulletin 2012/36 (21) Application number: 10827453.1 (22) Date of filing: 28.10.2010

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) A61P 25/00(2006.01) A61K 38/17(2006.01) (86) International application number: PCT/US2010/054419 (87) International publication number: WO 2011/053675 (05.05.2011 Gazette 2011/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 30.10.2009 US 256352 P (71) Applicants: CNS Therapeutics, Inc. Woodbury, MN 55125 (US) University Of Helsinki 00014 University Of Helsinki (FI)	(72) Inventors: RUNEBERG-ROOS, Pia Woodbury, MN 55125 (US) BESPALOV, Maxim Woodbury, MN 55125 (US) PENN, Richard Woodbury, MN 55125 (US) SAARMA, Mart Woodbury, MN 55125 (US) (74) Representative: Rutt, Jason Edward  Rouse Patents Patents Agency 11th Floor, Exchange Tower 1 Harbour Exchange Square London E14 9GE London E14 9GE (GB)