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EP 2 513 051 A1

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(43) Date of publication: 24.10.2012 Bulletin 2012/43 (21) Application number: 10796354.8 (22) Date of filing: 14.12.2010

(51) International Patent Classification (IPC):  C07D 205/08(2006.01) A61K 31/397(2006.01) A61P 35/00(2006.01) C07D 409/04(2006.01) A61K 31/381(2006.01) (86) International application number: PCT/EP2010/069670 (87) International publication number: WO 2011/073211 (23.06.2011 Gazette 2011/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 15.12.2009 EP 09179351 (71) Applicant: The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin Dublin 2 (IE)	(72) Inventors: MEEGAN, Mary J. Dublin 16 (IE) ZISTERER, Daniela Co. Wicklow (IE) CARR, Miriam Co. Limerick (IE) GREENE, Thomas Co. Tipperary (IE) O'BOYLE, Niamh Co. Kildare (IE) GREENE, Lisa 15 (IE) (74) Representative: Skrba, Sinéad et al Tomkins & Co. 5 Dartmouth Road 6 Dublin 6 Dublin (IE)