Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections

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EP 2 520 654 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	19.04.2017 Bulletin 2017/16

(45)	Mention of the grant of the patent:
	01.02.2017 Bulletin 2017/05

(21)	Application number: 12003146.3

(22)	Date of filing: 26.08.2004

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International Patent Classification (IPC):

C12N 15/62^(2006.01)
C07K 16/00^(2006.01)

C07K 14/81^(2006.01)
A61K 38/57^(2006.01)

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Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections

Serinprotease-Hemmer und deren Verwendung in Verfahren und Zusammensetzungen für die Behandlung bakterieller Infektionen

Inhibiteurs de l'activité de sérine protéase et leur utilisation dans des procédés et compositions pour le traitement des infections bactériennes

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

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Priority:

26.08.2003 US 497703 P

(43)	Date of publication of application:
	07.11.2012 Bulletin 2012/45

(60)	Divisional application:
	17000155.6

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	04801916.0 / 1660094

(73)	Proprietor: The Regents of the University of Colorado, a body corporate
	Denver, CO 80203 (US)

(72)	Inventor:
	Shapiro, Leland Denver, CO 80220 (US)

(74)	Representative: Bohmann, Armin K.
	Bohmann Anwaltssozietät Nymphenburger Straße 1 80335 München 80335 München (DE)

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References cited: :

WO-A1-01/03737
WO-A2-00/51623
WO-A2-03/059935

WO-A1-92/06706
WO-A2-02/060919
US-B1- 6 287 817

CHAN E D ET AL: "Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages", SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, SCANDINAVIAN UNIVERSITY PRESS, OSLO, NO, vol. 39, no. 8, 1 January 2007 (2007-01-01), pages 690-696, XP008108498, ISSN: 0036-5548, DOI: 10.1080/00365540701225744


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).