(19)

(11)

EP 2 525 651 A2

(12)

(88) Date of publication A3: 22.09.2011 (43) Date of publication: 28.11.2012 Bulletin 2012/48 (21) Application number: 11735284.9 (22) Date of filing: 21.01.2011

(51) International Patent Classification (IPC):  A01H 5/00(2006.01) (86) International application number: PCT/US2011/022168 (87) International publication number: WO 2011/091332 (28.07.2011 Gazette 2011/30)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 22.01.2010 US 297636 P (71) Applicant: Chromatin, Inc. Chicago, IL 60616 (US)	(72) Inventors: COPENHAVER, Gregory P. Chapel Hill North Carolina 27516 (US) LUO, Song Chicago Illinois 60615 (US) MACH, Jennifer Chicago Illinois 60641 (US) PREUSS, Daphne Chicago Illinois 60654 (US) RAMIREZ, Rolando Chicago Illinois 60647 (US) (74) Representative: Williams, Aylsa  D Young & Co LLP 120 Holborn London EC1N 2DY London EC1N 2DY (GB)