(19)

(11)

EP 2 525 786 A2

(12)

(88) Date of publication A3: 15.03.2012 (43) Date of publication: 28.11.2012 Bulletin 2012/48 (21) Application number: 11700346.7 (22) Date of filing: 17.01.2011

(51) International Patent Classification (IPC):  A61K 9/22(2006.01) A61K 31/428(2006.01) (86) International application number: PCT/EP2011/050542 (87) International publication number: WO 2011/086182 (21.07.2011 Gazette 2011/29)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 18.01.2010 US 296012 P (71) Applicant: Synthon BV 6545 CM Nijmegen (NL)	(72) Inventor: ABUKHALIL, Asad NL-6545 CM Nijmegen (NL) (74) Representative: van der Sterren-Mol, Josephine et al Synthon BV IP Research P.O. Box 7071 6503 GN Nijmegen 6503 GN Nijmegen (NL)