(19)
(11) EP 2 526 089 A2

(12)

(88) Date of publication A3:
22.09.2011

(43) Date of publication:
28.11.2012 Bulletin 2012/48

(21) Application number: 11707780.0

(22) Date of filing: 12.01.2011
(51) International Patent Classification (IPC): 
C07D 207/34(2006.01)
A61P 3/06(2006.01)
 A61K 31/40(2006.01)
(86) International application number:
PCT/CZ2011/000003
(87) International publication number:
WO 2011/088806 (28.07.2011 Gazette 2011/30)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 19.01.2010 CZ 20100039

(71) Applicant: Zentiva, K.S.
102 37 Praha 10 (CZ)

(72) Inventors:
  • STACH, Jan
    190 16 Praha 9 (CZ)
  • HOLAN, Martin
    109 00 Praha 15 (CZ)
  • HAVLICEK, Jaroslav
    149 00 Praha 4 (CZ)
  • SIMEK, Stanislav
    102 00 Praha 10 (CZ)
  • LINEK, Jan
    109 00 Praha 15 (CZ)
  • BRUSOVA, Hana
    197 00 Praha 9 (CZ)
  • RADL, Stanislav
    250 84 Kvetnice (CZ)
  • DUBOVSKA, Michaela
    101 00 Praha 10 (CZ)
  • PROKOPOVA, Alena
    101 00 Praha 10 (CZ)
  • RIHA, Jaroslav
    107 00 Praha 10 (CZ)
  • SEBEK, Pavel
    161 00 Praha 6 (CZ)

(74) Representative: Jirotkova, Ivana et al
Rott, Ruzicka & Guttmann Patent, Trademark and Law Offices Vinohradskà 37
120 00 Praha 2
120 00 Praha 2 (CZ)

   


(54) A METHOD OF INDUSTRIAL PRODUCTION OF AN AMORPHOUS FORM OF ATORVASTATIN WITH A HIGH SPECIFIC SURFACE AREA AND ITS USE IN A DOSAGE FORM