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EP 2 528 894 A1

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(43) Date of publication: 05.12.2012 Bulletin 2012/49 (21) Application number: 11703939.6 (22) Date of filing: 27.01.2011

(51) International Patent Classification (IPC):  C07D 209/94(2006.01) A61P 29/00(2006.01) A61K 31/403(2006.01) A61P 37/06(2006.01) (86) International application number: PCT/US2011/000153 (87) International publication number: WO 2011/094008 (04.08.2011 Gazette 2011/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 27.01.2010 US 336835 P (71) Applicant: Arena Pharmaceuticals, Inc. San Diego, CA 92121 (US)

(72) Inventors: MONTALBAN, Antonio, Garrido San Diego CA 92129 (US) BUZARD, Daniel, John San Diego CA 92129 (US) DeMATTEI, John, Aldo San Diego CA 92129 (US) GHARBAOUI, Tawfik Escondido CA 92029 (US) JOHANNSEN, Stephen, Robert San Diego CA 92107 (US) KRISHNAN, Ashwin, M. San Diego CA 92121 (US) KUHLMAN, Young, Mi San Diego CA 92131 (US) MA, You-An Poway CA 92064 (US) MARTINELLI, Michael, John San Diego CA 92130 (US) SATO, Suzanne, Michiko San Diego CA 92131 (US) SENGUPTA, Dipanjan San Diego CA 92129 (US) (74) Representative: Wytenburg, Wilhelmus Johannes et al Mewburn Ellis LLP 33 Gutter Lane GB-London EC2V 8AS GB-London EC2V 8AS (GB)