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(11)

EP 2 528 926 A1

(12)

(43) Date of publication: 05.12.2012 Bulletin 2012/49 (21) Application number: 11736580.9 (22) Date of filing: 24.01.2011

(51) International Patent Classification (IPC):  C07D 519/00(2006.01) A61K 31/444(2006.01) A61P 31/14(2006.01) A61K 31/439(2006.01) A61K 31/506(2006.01) (86) International application number: PCT/CA2011/050041 (87) International publication number: WO 2011/091532 (04.08.2011 Gazette 2011/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 26.04.2010 US 327900 P 28.01.2010 US 299186 P (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE)	(72) Inventors: KUHN, Cyrille Laval, Quebec H7S 2G5 (CA) BHARDWAJ, Punit K . Laval, Quebec H7S 2G5 (CA) POUPART, Marc-Andre Laval, Quebec H7S 2G5 (CA) (74) Representative: Simon, Elke Anna Maria et al Boehringer Ingelheim GmbH Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)