(19)

(11)

EP 2 531 203 A2

(12)

(88) Date of publication A3: 10.11.2011 (43) Date of publication: 12.12.2012 Bulletin 2012/50 (21) Application number: 11709470.6 (22) Date of filing: 28.01.2011

(51) International Patent Classification (IPC):  A61K 36/534(2006.01) A61P 31/00(2006.01) (86) International application number: PCT/IB2011/050386 (87) International publication number: WO 2011/092655 (04.08.2011 Gazette 2011/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 01.02.2010 IT RM20100035 (71) Applicant: Universita'Degli Studi di Roma "La Sapienza" 00185 Roma (IT)	(72) Inventors: ANGIOLELLA, Letizia I-00135 Roma RM (IT) RAGNO, Rino I-00125 Roma RM (IT) (74) Representative: Predazzi, Valentina et al Società Italiana Brevetti S.p.A. Piazza di Pietra, 39 00186 Roma 00186 Roma (IT)