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EP 2 531 596 A2

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(88) Date of publication A3: 01.12.2011 (43) Date of publication: 12.12.2012 Bulletin 2012/50 (21) Application number: 11714389.1 (22) Date of filing: 04.02.2011

(51) International Patent Classification (IPC):  C12N 9/24(2006.01) C12N 9/90(2006.01) C12R 1/645(2006.01) C12N 9/48(2006.01) C14C 1/06(2006.01) (86) International application number: PCT/IB2011/000178 (87) International publication number: WO 2011/095875 (11.08.2011 Gazette 2011/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 05.02.2010 IN DE02492010 (71) Applicant: Council of Scientific & Industrial Research New Delhi 110 001 (IN)

(72) Inventors: RYALI, Seeta, Laxman 411008 Pune (Maharashtra) (IN) SHANKAR, Shiv 411008 Pune (Maharashtra) (IN) MORE, Snehal, Vijay 411008 Pune (Maharashtra) (IN) KHANDELWAL, Harish, Bansilal 411008 Pune (Maharashtra) (IN) NARASIMHAN, Chandra, Babu, Kannan Tamil Nadu (IN) PALANIVEL, Saravanan Tamil Nadu (IN) BALARAM, Padmanabhan 560012 Bangalore Karnataka (IN) (74) Representative: Arends, William Gerrit  Marks & Clerk LLP 90 Long Acre London WC2E 9RA London WC2E 9RA (GB)