PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF

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EP 2 536 283 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	04.11.2015 Bulletin 2015/45

(45)	Mention of the grant of the patent:
	29.07.2015 Bulletin 2015/31

(21)	Application number: 11745116.1

(22)	Date of filing: 15.02.2011

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International Patent Classification (IPC):

C07D 401/12^(2006.01)
C07D 413/14^(2006.01)
C07D 403/12^(2006.01)
A61K 31/501^(2006.01)
A61P 29/00^(2006.01)

C07D 407/14^(2006.01)
C07D 401/14^(2006.01)
C07D 413/06^(2006.01)
A61P 25/00^(2006.01)
A61P 35/00^(2006.01)

(86)	International application number:
	PCT/US2011/024886

(87)	International publication number:
	WO 2011/103091 (25.08.2011 Gazette 2011/34)

(54)	PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF PHENYLHETEROARYLDERIVATE UND VERWENDUNGSVERFAHREN DAFÜR DÉRIVÉS DE PHÉNYL-HÉTÉROARYLE ET PROCÉDÉS D'UTILISATION DE CEUX-CI

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME

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Priority:

18.02.2010 US 305572 P

(43)	Date of publication of application:
	26.12.2012 Bulletin 2012/52

(73)	Proprietor: vTv Therapeutics LLC
	High Point, NC 27265 (US)

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Inventors:

GOHIMUKKULA, Devi, Reddy
Jamestown, North Carolina 27282 (US)
JONES, David
Milford, Ohio 45150 (US)
QABAJA, Ghassan
Jamestown, North Carolina 27282 (US)
ZHU, Jeff, Jiqun
Winston-Salem, NC 27127 (US)
COOPER, Jeremy, T.
High Point, North Carolina 27265 (US)
BANNER, William, Kenneth
Greensboro, North Carolina 27407 (US)
SUNDERMANN, Kurt
Summerfield, North Carolina 27358 (US)
BONDLELA, Muralidhar
Greensboro, North Carolina 27410 (US)
RAO, Mohan
Greensboro, North Carolina 27410 (US)
WANG, Pingzhen
Kernersville, North Carolina 27284 (US)
GOWDA, Raju, Bore
Oak Ridge, North Carolina 27310 (US)
ANDREWS, Robert, C.
Jamestown, North Carolina 27282 (US)
GUPTA, Suparna
Greensboro, North Carolina 27455 (US)
HARI, Anitha
High Point, North Carolina 27265 (US)

(74)	Representative: D Young & Co LLP
	120 Holborn London EC1N 2DY London EC1N 2DY (GB)

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References cited: :

WO-A1-2008/098892
US-A- 4 008 232
US-A1- 2006 160 804
US-A1- 2008 275 050
US-A1- 2009 298 853
US-B1- 6 664 256

US-A- 2 728 768
US-A- 5 449 676
US-A1- 2007 213 347
US-A1- 2009 275 589
US-B1- 6 664 256
US-B2- 7 087 632

TANAKA A ET AL: "Studies on anti-platelet agents. V. Synthesis and structure-activity relationship of 3-substituted 5,6-bis(4-methoxyphenyl)-1,2,4- triazines", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN, JP, vol. 42, no. 9, 1 January 1994 (1994-01-01), pages 1835-1840, XP002274901, ISSN: 0009-2363
WUSTROW D J ET AL: "Aminopyrazine CB1 receptor inverse agonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 18, no. 11, 1 June 2008 (2008-06-01), pages 3376-3381, XP022711231, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2008.04.022 [retrieved on 2008-04-13]

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).