(19)

(11)

EP 2 538 848 A2

(12)

(88) Date of publication A3: 20.10.2011 (43) Date of publication: 02.01.2013 Bulletin 2013/01 (21) Application number: 11707315.5 (22) Date of filing: 25.02.2011

(51) International Patent Classification (IPC):  A61B 17/00(2006.01) A61F 2/82(2013.01) A61F 2/90(2013.01) (86) International application number: PCT/US2011/026335 (87) International publication number: WO 2011/106713 (01.09.2011 Gazette 2011/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 21.12.2010 US 974543 21.12.2010 US 974489 21.12.2010 US 974453 21.12.2010 US 974414 21.07.2010 US 841100 21.07.2010 US 841083 21.07.2010 US 841073 21.07.2010 US 841052 10.06.2010 US 353561 P 26.02.2010 US 308859 P (71) Applicant: Promed, Inc. Santa Clara, CA 95050 (US)

(72) Inventors: GINN, Richard, S. Gilroy, California 95020 (US) DOMINGO, Nicanor Santa Clara, California 95054 (US) VALENCIA, Hans, F. San Jose, California 95126 (US) DECOU, Robert, Elliott San Jose, California 95128 (US) YERBY, Scott Montara, California 94037 (US) (74) Representative: Price, Nigel John King  J A Kemp 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)