(19)

(11)

EP 2 542 264 A1

(12)

(43) Date of publication: 09.01.2013 Bulletin 2013/02 (21) Application number: 11712753.0 (22) Date of filing: 04.03.2011

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) A61N 1/40(2006.01) A61K 49/18(2006.01) (86) International application number: PCT/EP2011/001089 (87) International publication number: WO 2011/107290 (09.09.2011 Gazette 2011/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 04.03.2010 IT LI20100001 (71) Applicants: Advanced Catalysts S.r.l. 56126 Pisa (IT) Dipartimento Di Medicina Interna 56126 Pisa (IT) Società Medico Chirurgica Livornese 57124 Livorno (IT)	(72) Inventors: BARBARO, Daniele I-57125 Livorno (IT) MONZANI, Fabio I-56125 Pisa (IT) DI BARI, Lorenzo I-56125 Pisa (IT) EVANGELISTI, Claudio I-56125 Pisa (IT) SALVADORI, Piero I-56100 Pisa (IT) VITULLI, Giovanni I-57126 Pisa (IT) URSINO, Silvia I-56021 Cascina PI (IT) (74) Representative: Celestino, Marco  ABM Agenzia Brevetti & Marchi, Viale Giovanni Pisano, 31 56123 Pisa 56123 Pisa (IT)