| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
|
Designated Extension States: |
|
BA ME |
| (30) |
Priority: |
08.01.2010 US 293612 P
|
| (43) |
Date of publication of application: |
|
09.01.2013 Bulletin 2013/02 |
| (73) |
Proprietors: |
|
- Progastrine et Cancers S.à r.l.
1450 Luxembourg (LU)
- INSTITUT NATIONAL DE LA SANTE ET
DE LA RECHERCHE MEDICALE (INSERM)
75654 Paris Cédex 13 (FR)
- Centre National de la Recherche Scientifique
(C.N.R.S.)
75794 Paris Cedex 16 (FR)
|
|
| (72) |
Inventors: |
|
- HOUHOU, Leïla
34090 Montpellier (FR)
- JOUBERT, Dominique
34200 Sète (FR)
- HOLLANDE, Frédéric
34790 Grabels (FR)
|
| (74) |
Representative: Regimbeau |
|
La Coupole Sud
379, rue Léon Blum
34000 Montpellier
34000 Montpellier (FR) |
| (56) |
References cited: :
WO-A1-2006/032980
WO-A2-2008/063479
|
WO-A1-2008/076454
US-B1- 6 548 066
|
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| |
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- GOETZE J P ET AL: "Closing the gastrin loop in pancreatic carcinoma: coexpression
of gastrin and its receptor in solid human pancreatic adenocarcinoma.", CANCER 1 JUN
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XP002625535, ISSN: 0008-543X
- CAPLIN M ET AL: "Expression and processing of gastrin in pancreatic adenocarcinoma.",
THE BRITISH JOURNAL OF SURGERY AUG 2000 LNKD- PUBMED:10931047, vol. 87, no. 8, August
2000 (2000-08), pages 1035-1040, XP002625536, ISSN: 0007-1323
- MATTERS GAIL L ET AL: "Growth of human pancreatic cancer is inhibited by down-regulation
of gastrin gene expression.", PANCREAS JUL 2009 LNKD- PUBMED:19465883, vol. 38, no.
5, July 2009 (2009-07), pages E151-E161, XP002625537, ISSN: 1536-4828
- SMITH J P ET AL: "Identification of gastrin as a growth peptide in human pancreatic
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no. 1 Pt 2, January 1995 (1995-01), pages R135-R141, XP9145263, ISSN: 0002-9513
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47-52, XP002398546, ISSN: 0017-5749, DOI: DOI:10.1136/GUT.48.1.47
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Gastrins and Expression of Apoptosis-Related Proteins in Colorectal Cancer", DIGESTIVE
DISEASES AND SCIENCES, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 51,
no. 4, 1 April 2006 (2006-04-01), pages 779-787, XP019277199, ISSN: 1573-2568
- BARDRAM L: "PROGASTRIN IN SERUM FROM ZOLLINGER-ELLISON PATIENTS AN INDICATOR OF MALIGNANCY?",
GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 98, no. 6, 1 January 1990 (1990-01-01),
pages 1420-1426, XP001053157, ISSN: 0016-5085
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