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EP 2 545 025 A1

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(43) Date of publication: 16.01.2013 Bulletin 2013/03 (21) Application number: 11709279.1 (22) Date of filing: 09.03.2011

(51) International Patent Classification (IPC):  C07C 46/06(2006.01) A61K 9/00(2006.01) A61P 25/00(2006.01) A61P 13/12(2006.01) A61P 3/10(2006.01) C07D 311/72(2006.01) A61K 31/125(2006.01) A61P 9/00(2006.01) A61P 27/02(2006.01) (86) International application number: PCT/US2011/027690 (87) International publication number: WO 2011/112679 (15.09.2011 Gazette 2011/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 09.03.2010 US 312185 P (71) Applicant: Edison Pharmaceuticals, Inc. Mountain View, CA 94043 (US)	(72) Inventors: PAISLEY, Steven, D. Patterson, NY 12563 (US) LEPREE, Jason, M. Patterson, NY 12563 (US) HAWI, Amale Patterson, NY 12563 (US) ECKHOFF, Michael Patterson, NY 12563 (US) (74) Representative: Sexton, Jane Helen  J A Kemp 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)