(19)

(11)

EP 2 549 988 A1

(12)

(43) Date of publication: 30.01.2013 Bulletin 2013/05 (21) Application number: 11709445.8 (22) Date of filing: 23.03.2011

(51) International Patent Classification (IPC):  A61K 9/70(2006.01) A61K 31/403(2006.01) A61K 31/00(2006.01) A61K 31/715(2006.01) (86) International application number: PCT/EP2011/054482 (87) International publication number: WO 2011/117313 (29.09.2011 Gazette 2011/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 23.03.2010 EP 10305288 23.03.2010 US 729735 (71) Applicant: APR APPLIED PHARMA RESEARCH S.A. 6828 Balerna (CH)	(72) Inventor: COSTANTINI, Dominique F-75014 Paris (FR) (74) Representative: Jacobson, Claude  Cabinet Lavoix 2, Place d'Estienne d'Orves 75441 Paris Cedex 09 75441 Paris Cedex 09 (FR)