(19)
(11) EP 2 552 491 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
18.04.2018 Bulletin 2018/16

(45) Mention of the grant of the patent:
07.03.2018 Bulletin 2018/10

(21) Application number: 11714127.5

(22) Date of filing: 01.04.2011
(51) International Patent Classification (IPC): 
A61K 49/00(2006.01)
A61K 9/00(2006.01)
(86) International application number:
PCT/NL2011/050218
(87) International publication number:
WO 2011/122947 (06.10.2011 Gazette 2011/40)

(54)

STAINING COMPOSITION FOR USE IN A METHOD OF EYE SURGERY

FARBZUSAMMENSETZUNG ZUR VERWENDUNG IN EINEM VERFAHREN DER AUGENCHIRURGIE

COMPOSITION DE COLORATION POUR L'UTILISATION DANS UNE MÉTHODE CHIRURGICALE DE L'OEIL


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 03.06.2010 EP 10164866
01.04.2010 EP 10159021

(43) Date of publication of application:
06.02.2013 Bulletin 2013/06

(73) Proprietor: D.O.R.C. Dutch Ophthalmic Research Center (International) B.V.
3214 VN Zuidland (NL)

(72) Inventor:
  • MELLES, Gerrit Reinold Jacob
    NL-3071 MJ Rotterdam (NL)

(74) Representative: V.O. 
P.O. Box 87930
2508 DH Den Haag
2508 DH Den Haag (NL)


(56) References cited: : 
EP-A1- 1 132 065
WO-A2-2010/078942
WO-A2-2011/110347
WO-A1-86/02548
WO-A2-2011/109214
US-A1- 2004 019 010
   
  • KUDO K ET AL: "Avoiding vitreous staining as a complication of trypan blue capsule staining", FOLIA OPHTHALMOLOGICA JAPONICA, OSAKA, JP, vol. 56, no. 3, 1 January 2005 (2005-01-01), pages 168-171, XP008088289, ISSN: 0015-5667
  • VECKENEER M ET AL: "Ocular toxicity study of trypan blue injected into the vitreous cavity of rabbit eyes", GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, SPRINGER VERLAG, XX, vol. 239, no. 9, 1 January 2001 (2001-01-01), pages 698-704, XP002268940, ISSN: 0721-832X
  • LESNIK OBERSTEIN S Y ET AL: "Heavy trypan blue staining of epiretinal membranes: An alternative to infracyanine green", BRITISH JOURNAL OF OPHTHALMOLOGY 200707 GB, vol. 91, no. 7, July 2007 (2007-07), pages 955-957, ISSN: 0007-1161
  • BARBOSA H ET AL: "Protein quantification in the presence of poly(ethylene glycol) and dextran using the Bradford method", 1 December 2009 (2009-12-01), ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, PAGE(S) 108 - 110, XP026626779, ISSN: 0003-2697 [retrieved on 2009-08-03]
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).