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EP 2 552 933 A1

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(43) Date of publication: 06.02.2013 Bulletin 2013/06 (21) Application number: 11714467.5 (22) Date of filing: 31.03.2011

(51) International Patent Classification (IPC):  C07H 19/20(2006.01) A61P 31/14(2006.01) A61K 31/7076(2006.01) (86) International application number: PCT/US2011/030767 (87) International publication number: WO 2011/123672 (06.10.2011 Gazette 2011/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 31.03.2010 US 319548 P 17.06.2010 US 355940 P (71) Applicant: Gilead Pharmasset LLC Foster City, CA 94404 (US)

(72) Inventors: CHANG, Wonsuk Princeton NJ 08540 (KP) NADUTHAMBI, Devan Plainsboro, NJ 08536 (US) NAGARATHNAM, Dhanapalan Bethany, CT 06524 (US) PAMULAPATI, Ganapati, Reddy Plainsboro, NJ 08536 (US) ROSS, Bruce, S. Plainaboro, NJ 08536 (US) SOFIA, Michael, Joseph Doylestown, PA 18901 (US) ZHANG, Hai-Ren Ellicott City, MD 21043 (US) (74) Representative: Schwarz & Partner  Patentanwälte Wipplingerstraße 30 1010 Wien 1010 Wien (AT)