(19)

(11)

EP 2 557 923 A1

(12)

(43) Date of publication: 20.02.2013 Bulletin 2013/08 (21) Application number: 11769663.3 (22) Date of filing: 15.04.2011

(51) International Patent Classification (IPC):  A01N 43/26(2006.01) A61K 31/385(2006.01) A61K 31/38(2006.01) (86) International application number: PCT/US2011/032683 (87) International publication number: WO 2011/130628 (20.10.2011 Gazette 2011/42)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 16.04.2010 US 324912 P (71) Applicant: Curis, Inc. Lexington, MA 02421 (US)	(72) Inventors: BAO, Rudi Wellesley MA 02482 (US) LAI, Chengjung Belmont MA 02478 (US) QIAN, Changgeng Wayland MA 01778 (US) (74) Representative: Simpson, Mark Geoffrey  Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG Nottingham NG1 5GG (GB)