(19)

(11)

EP 2 558 479 A1

(12)

(43) Date of publication: 20.02.2013 Bulletin 2013/08 (21) Application number: 11763339.6 (22) Date of filing: 29.03.2011

(51) International Patent Classification (IPC):  C07H 21/00(2006.01) C12P 19/34(2006.01) (86) International application number: PCT/US2011/030398 (87) International publication number: WO 2011/123473 (06.10.2011 Gazette 2011/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 29.03.2010 US 318417 P (71) Applicant: Han, Jian Huntsville, Alabama 37215 (US)	(72) Inventor: Han, Jian Huntsville, Alabama 37215 (US) (74) Representative: Webber, Philip Michael et al Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)