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(11)

EP 2 563 902 A1

(12)

(43) Date of publication: 06.03.2013 Bulletin 2013/10 (21) Application number: 11716840.1 (22) Date of filing: 27.04.2011

(51) International Patent Classification (IPC):  C12N 1/19(2006.01) C07H 21/04(2006.01) C12N 1/16(2006.01) C12P 21/02(2006.01) C12N 1/18(2006.01) (86) International application number: PCT/EP2011/002094 (87) International publication number: WO 2011/134643 (03.11.2011 Gazette 2011/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 27.04.2010 WO PCT/EP2010/002570 (71) Applicant: Lonza Ltd 3930 Visp (CH)	(72) Inventors: AEBI, Markus CH-5430 Wettingen (CH) PARSAIE NASAB, Farnoush CH-8049 Zuerich (CH) FREY, Alexander, Daniel CH-4600 Olten (CH) (74) Representative: Schrell, Andreas et al Gleiss Grosse Schrell & Partner Patentanwälte Rechtsanwälte Leitzstrasse 45 70469 Stuttgart 70469 Stuttgart (DE)