(19)
(11) EP 2 566 866 A1

(12)

(43) Date of publication:
13.03.2013 Bulletin 2013/11

(21) Application number: 10721216.9

(22) Date of filing: 05.05.2010
(51) International Patent Classification (IPC): 
C07D 487/04(2006.01)
A61P 37/00(2006.01)
 A61K 31/519(2006.01)
(86) International application number:
PCT/US2010/033711
(87) International publication number:
WO 2011/139273 (10.11.2011 Gazette 2011/45)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(71) Applicant: Vertex Pharmaceuticals Incorporated
Cambridge, MA 02139 (US)

(72) Inventors:
  • JIMENEZ, Juan-miguel
    Abingdon, Oxfordshire OX14 4RY (GB)
  • MILLER, Andrew
    Abingdon, Oxfordshire OX14 4RY (GB)

(74) Representative: Coles, Andrea Birgit et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) 4 SUBSTITUTED PYRAZOLOPYRIMIDINES USEFUL AS PKC-THETA INHIBITORS