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EP 2 569 298 A1

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(43) Date of publication: 20.03.2013 Bulletin 2013/12 (21) Application number: 11719249.2 (22) Date of filing: 10.05.2011

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) C07D 413/14(2006.01) C07D 491/10(2006.01) C07D 471/04(2006.01) A61K 31/506(2006.01) A61P 37/00(2006.01) A61P 25/00(2006.01) C07D 405/14(2006.01) C07D 487/04(2006.01) C07D 495/04(2006.01) A61K 31/4725(2006.01) A61K 31/5377(2006.01) A61P 9/00(2006.01) (86) International application number: PCT/EP2011/057545 (87) International publication number: WO 2011/141474 (17.11.2011 Gazette 2011/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 12.05.2010 EP 10162629 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE)

(72) Inventors: EBEL, Heiner 55216 Ingelheim Am Rhein (DE) FRATTINI, Sara 55216 Ingelheim Am Rhein (DE) GIOVANNINI, Riccardo 55216 Ingelheim Am Rhein (DE) HOENKE, Christoph 55216 Ingelheim Am Rhein (DE) MAZZAFERRO, Rocco 55216 Ingelheim Am Rhein (DE) SCHEUERER, Stefan 55216 Ingelheim Am Rhein (DE) (74) Representative: Simon, Elke Anna Maria  Boehringer Ingelheim GmbH Corporate Patents Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)