ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*JBDM Ver 0.1.63 (23 May 2017) - 2999001/02569628FASCICULE DE BREVET EUROPEEN CORRIGEB8B120190424W173deBibliographieenBibliographyfrBibliographieEP11719026.4201105122012120720150105frfrfr105373220100512FR2019042420191720130320201312201811072018452018052820190424201917G01N 33/50 20060101AFI20111220BHEP G06F 19/00 20180101ALI20111220BHEP deTOXIKOLOGISCHES BEURTEILUNGSVERFAHRENenSYSTEM FOR TOXICOLOGICAL EVALUATION AND TOXICOGENOMICSfrPROCÉDÉ D'ÉVALUATION TOXICOLOGIQUE, PROCÉDÉ DE CRIBLAGE TOXICOLOGIQUE ET SYSTÈME ASSOCIÉBORLON CÉLINE ET AL: "The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis.", TOXICOLOGY, vol. 241, no. 3, 30 novembre 2007 (2007-11-30), pages 157-166, XP002614420, ISSN: 0300-483XBOLLARD MARY E ET AL: "Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy.", CHEMICAL RESEARCH IN TOXICOLOGY, vol. 15, no. 11, novembre 2002 (2002-11), pages 1351-1359, XP002614421, ISSN: 0893-228XSEAGLE CHRISTOPHER ET AL: "High-throughput nuclear magnetic resonance metabolomic footprinting for tissue engineering.", TISSUE ENGINEERING. PART C, METHODS, vol. 14, no. 2, juin 2008 (2008-06), pages 107-118, XP002614422, ISSN: 1937-3384VAN VLIET ET AL: "A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine", NEUROTOXICOLOGY, TOX PRESS, RADFIELD, AR, IN, vol. 29, no. 1, 1 janvier 2008 (2008-01-01), pages 1-12, XP022417840, ISSN: 0161-813X, DOI: DOI:10.1016/J.NEURO.2007.09.007Ioro et al: "Statistical Techniques in Metabolic Profiling" In: Balding et al: "Handbook of statistical genetics", 2007, John Wiley & Sons, XP002614423, ISBN: 9780470058305 pages 347-373, 55, para 11.3.1 - pg 357, para 11.3.2DAYKIN ET AL: "NMR spectroscopy based metabonomics: current technology and applications", FRONTIERS IN DRUG DESIGN & DISCOVERY, vol. 2, 2006, pages 151-173, XP8130643,BRYAN KENNETH ET AL: "MetaFIND: a feature analysis tool for metabolomics data.", BMC BIOINFORMATICS, vol. 9, 470, 2008, pages 1-13, XP002614425, ISSN: 1471-2105THYSELL ELIN ET AL: "Reliable profile detection in comparative metabolomics.", OMICS : A JOURNAL OF INTEGRATIVE BIOLOGY SUMMER, vol. 11, no. 2, juillet 2007 (2007-07), pages 209-224, XP002614426, ISSN: 1536-2310BAUDOIN ET AL: "Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity", TOXICOLOGY IN VITRO, ELSEVIER SCIENCE, GB, vol. 21, no. 4, 10 avril 2007 (2007-04-10) , pages 535-544, XP022025268, ISSN: 0887-2333, DOI: 10.1016/J.TIV.2006.11.004FARKAS DORA ET AL: "In vitro methods to study chemically-induced hepatotoxicity: a literature review.", CURRENT DRUG METABOLISM, vol. 6, no. 2, avril 2005 (2005-04), pages 111-125, XP8094939, ISSN: 1389-2002R Baudoin: "Développement et caractérisation d'une puce à cellules pour le criblage d'agents toxiques", HAL, 1 January 2008 (2008-01-01), pages 1-188, XP055467427, DOI: 10.1016/j.comgeo.2016.07.001 Retrieved from the Internet: URL:https://tel.archives-ouvertes.fr/tel-0 0342342/document [retrieved on 2018-04-16]DUMAS, Marc-Emmanuel66 Portland GroveLondres SW8 1JQGBLECLERC, Eric85 rue Maréchal FochF-60280 Margny Les CompiegneFRSHINTU, Laetitia47 rue d'AlgerF-13005 MarseilleFRBAUDOIN, Regis21 rue du pré de l'ArcheF-93360 Neuilly PlaisanceFRLEGALLAIS, Cécile15 rue du Château d'EauF-60340 Villers Sous Saint LeuFRTOULHOAT, Pierre20 avenue Charles de GaulleF-69370 Saint Didier au Mont d'OrFRBROCHOT, Céline11 allée de BruxellesF-60340 Villers Sous Saint LeuFRUniversité de technologie de Compiègne (UTC)10180439570315D28290Rue du docteur Schweitzer60200 CompiègneFRCentre National de la Recherche Scientifique (CNRS)10162041470315D282903, rue Michel Ange75016 ParisFREcole Normale Supérieure de Lyon10127802370315D2829015 parvis René Descartes69007 LyonFRInstitut National De L'environnement Industriel Et Des Risques10117762370315D28290Parc Technologique Alata B.P. N°260550 Verneuil-en-HalatteFRRegimbeau10132651920, rue de Chazelles75847 Paris Cedex 17FRALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTREP201105772020110512frWO201115114820111208201149