(19)
(11) EP 2 574 341 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 A1)

(48) Corrigendum issued on:
22.05.2013 Bulletin 2013/21

(88) Date of publication A3:
03.04.2013 Bulletin 2013/14

(43) Date of publication:
03.04.2013 Bulletin 2013/14

(21) Application number: 12197499.2

(22) Date of filing: 29.03.2005
(51) International Patent Classification (IPC): 
A61K 31/7064(2006.01)
A61P 35/00(2006.01)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

(30) Priority: 29.03.2004 US 557599 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
05746910.8 / 1737472

(71) Applicant: UNIVERSITY OF SOUTH FLORIDA
Tampa, FL 33612 (US)

(72) Inventors:
  • Cheng, Jin Q.
    Tampa, FL Florida 33647 (US)
  • Sebti, Said M.
    Tampa, FL Florida 33647 (US)

(74) Representative: Fanelli Haag Kilger PLLC 
Fasanenstrasse 29
10719 Berlin
10719 Berlin (DE)

 
Remarks:
This application was filed on 17-12-2012 as a divisional application to the application mentioned under INID code 62.
 


(54) Effective treatment of tumors and cancer with triciribine and related compounds


(57) The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine only to patients which according to a diagnostic test described below, exhibit enhanced sensitivity to the drug, (ii) use of a described dosage level that minimizes the toxicity of the drug but yet still exhibits efficacy; or (iii) use of a described dosage regiment that minimizes the toxicity of the drug.