| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
04.06.2010 EP 10164948
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| (43) |
Date of publication of application: |
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10.04.2013 Bulletin 2013/15 |
| (73) |
Proprietor: Life Molecular Imaging SA |
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1753 Matran (CH) |
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| (72) |
Inventors: |
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- BERNDT, Mathias
12163 Berlin (DE)
- FRIEBE, Matthias
13509 Berlin (DE)
- HULTSCH, Christina
12101 Berlin (DE)
- SAMSON, Fabrice
Seoul 140-858 (KR)
- OH, Seung, Jun
Seoul 150-045 (KR)
- SMUDA, Christoph
CH-8952 Schlieren (CH)
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| (74) |
Representative: Kilger, Ute |
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Boehmert & Boehmert
Anwaltspartnerschaft mbB
Pettenkoferstrasse 22 80336 München 80336 München (DE) |
| (56) |
References cited: :
WO-A1-2010/078370 WO-A2-2010/000409 US-A1- 2010 113 763
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WO-A1-2011/003591 US-A1- 2006 269 473
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- ZHANG ET AL: "F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Abeta
aggregates in the brain", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 32,
no. 8, 1 November 2005 (2005-11-01), pages 799-809, XP005129336, ISSN: 0969-8051,
DOI: 10.1016/J.NUCMEDBIO.2005.06.001 cited in the application
- WANG H ET AL: "Facile and rapid one-step radiosynthesis of [<18>F]BAY94-9172 with
a new precursor", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 38, no. 1,
1 January 2011 (2011-01-01), pages 121-127, XP027589497, ISSN: 0969-8051 [retrieved
on 2010-08-16] cited in the application
- PATT M ET AL: "Metabolite analysis of [18F]Florbetaben (BAY 94-9172) in human subjects:
a substudy within a proof of mechanism clinical trial", JOURNAL OF RADIOANALYTICAL
AND NUCLEAR CHEMISTRY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 284, no. 3, 16 March 2010
(2010-03-16), pages 557-562, XP019792449, ISSN: 1588-2780
- LIN K J ET AL: "Whole-body biodistribution and brain PET imaging with [<18>F]AV-45,
a novel amyloid imaging agent - a pilot study", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER,
NY, US, vol. 37, no. 4, 1 May 2010 (2010-05-01), pages 497-508, XP027039103, ISSN:
0969-8051 [retrieved on 2010-04-07]
- LIU Y ET AL: "Optimization of automated radiosynthesis of [<18>F]AV-45: a new PET
imaging agent for Alzheimer's disease", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY,
US, vol. 37, no. 8, 1 November 2010 (2010-11-01), pages 917-925, XP027472064, ISSN:
0969-8051, DOI: 10.1016/J.NUCMEDBIO.2010.05.001 [retrieved on 2010-06-29] cited in
the application
- YAO C H ET AL: "GMP-compliant automated synthesis of [<18>F]AV-45 (Florbetapir F 18)
for imaging beta-amyloid plaques in human brain", APPLIED RADIATION AND ISOTOPES,
ELSEVIER, OXFORD, GB, vol. 68, no. 12, 1 December 2010 (2010-12-01), pages 2293-2297,
XP027265706, ISSN: 0969-8043 [retrieved on 2010-07-07] cited in the application
- PIYUSH KUMAR ET AL: "18F-FESB: synthesis and automated radiofluorination of a novel18F-labeled
pet tracer for[beta]-amyloid plaques", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS,
vol. 48, no. 13, 1 November 2005 (2005-11-01), pages 983-996, XP55006268, ISSN: 0362-4803,
DOI: 10.1002/jlcr.1011
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