ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCY..TRBGCZEEHUPLSK..HRIS..MTNO........................JDIM360 Ver 2.40 (30 Jan 2013) - 1620000/02581456EUROPEAN PATENT APPLICATIONA320130717EP13150743.620090116enenen21756 P20080117US2013071720132920130417201316C12Q 1/68 20060101AFI20130607BHEP G06F 19/18 20110101ALI20130607BHEP deGenetische Marker von GeisteskrankheitenenGenetic Markers of Mental IllnessfrMarqueurs génétiques de maladie mentaleNONE09702855.9223187220090116Suregene Llc101122888PC925525EPD1044 East Chestnut Street, Suite 7Louisville, KY 40204USBrennan, Mark David3920 Charlestown PikeJeffersonville, IN 47130USRamsey, Timothy Lynn2803 Antioch RoadShelbyville, KY 40065USWilliams, Gareth Owen100051400Marks & Clerk LLP 62-68 Hills RoadCambridge CB2 1LAGBATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTROSESISKTR20130717201329

This invention relates to genetic markers of mental illness, e.g., schizophrenia (SZ), and methods of use thereof. In particular, in vitro methods of predicting a human subject's likely response to treatment with risperidone, quetiapine, perphenazine, or ziprasidone, or of selecting a treatment for schizophrenia comprising administration of risperidone, quetiapine, perphenazine, or ziprasidone, comprising detecting a haplotype comprising one or more polymorphic markers in CDH11 or markers in linkage disequilibrium (LD) therewith, are provided.

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