(19)
(11) EP 2 582 717 A2

(12)

(43) Date of publication:
24.04.2013 Bulletin 2013/17

(21) Application number: 11736219.4

(22) Date of filing: 15.06.2011
(51) International Patent Classification (IPC): 
C07K 14/435(2006.01)
(86) International application number:
PCT/US2011/040568
(87) International publication number:
WO 2011/159826 (22.12.2011 Gazette 2011/51)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 15.06.2010 US 355014 P
23.06.2010 US 357850 P

(71) Applicant: Vertex Pharmaceuticals Incorporated
Cambridge, MA 02139 (US)

(72) Inventors:
  • BARTELS, Douglas, J.
    North Liberty, IA 52317 (US)
  • JIANG, Min
    Lexington, MA 02420 (US)
  • KIEFFER, Tara, Lynn
    Brookline, MA 02446 (US)
  • NICOLAS, Olivier
    Montreal, QC H3L 2J1 (CA)

(74) Representative: Cabinet Plasseraud 
52, rue de la Victoire
75440 Paris Cedex 09
75440 Paris Cedex 09 (FR)

   


(54) HCV NS5B POLYMERASE MUTANTS