(19)
(11) EP 2 588 027 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
26.07.2017 Bulletin 2017/30

(45) Mention of the grant of the patent:
08.03.2017 Bulletin 2017/10

(21) Application number: 11801504.9

(22) Date of filing: 01.07.2011
(51) International Patent Classification (IPC): 
C12N 5/00(2006.01)
C12N 5/071(2010.01)
C12N 5/09(2010.01)
A61L 27/36(2006.01)
(86) International application number:
PCT/US2011/042825
(87) International publication number:
WO 2012/003463 (05.01.2012 Gazette 2012/01)

(54)

BIOMATRIX SCAFFOLDS FOR INDUSTRIAL SCALE DISPERSAL

BIOMATRIXGERÜSTE ZUR DISPERGIERUNG INDUSTRIELLER ABLAGERUNGEN

ÉCHAFAUDAGES DE BIOMATRICE POUR DISPERSION À L'ÉCHELLE INDUSTRIELLE


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 02.07.2010 US 360939 P

(43) Date of publication of application:
08.05.2013 Bulletin 2013/19

(60) Divisional application:
16191506.1

(73) Proprietors:
  • The University of North Carolina at Chapel Hill
    Chapel Hill, NC 27517 (US)
  • Roach, Marsha Lynn
    Branford, CT 06405 (US)
  • Malavarca, Richard Harold
    Long Valley, NJ 07853 (US)

(72) Inventors:
  • ROACH, Marsha Lynn
    Bradford, Connecticut 06405 (US)
  • MALAVARCA, Richard Harold
    Long Valley, New Jersey 07853 (US)
  • WANG, Yunfang
    Beijing 100850 (CN)
  • REID, Lola Cynthia McAdams
    Chapel Hill, North Carolina 27514 (US)

(74) Representative: HGF Limited 
1 City Walk
Leeds LS11 9DX
Leeds LS11 9DX (GB)


(56) References cited: : 
WO-A2-2010/039823
US-A1- 2005 058 631
US-A1- 2007 269 886
US-A1- 2002 177 551
US-A1- 2007 154 552
US-A1- 2009 060 961
   
  • E. A. ROSS ET AL: "Embryonic Stem Cells Proliferate and Differentiate when Seeded into Kidney Scaffolds", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol. 20, no. 11, 1 November 2009 (2009-11-01), pages 2338-2347, XP55074894, ISSN: 1046-6673, DOI: 10.1681/ASN.2008111196
  • THOMAS SHUPE: "Method for the decellularization of intact rat liver", ORGANOGENESIS, vol. 6, no. 2, 1 April 2010 (2010-04-01), pages 134-136, XP055083014,
  • YUNFANG WANG ET AL: "Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds", HEPATOLOGY, vol. 53, no. 1, 1 January 2011 (2011-01-01), pages 293-305, XP55074897, ISSN: 0270-9139, DOI: 10.1002/hep.24012
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).