NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA

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EP 2 590 651 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	08.08.2018 Bulletin 2018/32

(45)	Mention of the grant of the patent:
	27.06.2018 Bulletin 2018/26

(21)	Application number: 11740859.1

(22)	Date of filing: 06.07.2011

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International Patent Classification (IPC):

A61K 31/496^(2006.01)
A61K 31/663^(2006.01)
A61K 31/7056^(2006.01)
A61P 33/00^(2006.01)

A61K 31/664^(2006.01)
A61K 31/662^(2006.01)
A61P 33/06^(2006.01)

(86)	International application number:
	PCT/EP2011/061447

(87)	International publication number:
	WO 2012/004324 (12.01.2012 Gazette 2012/02)

(54)	NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA NEUE KOMBINATIONSPRÄPARATE ZUR BEHANDLUNG VON MALARIA NOUVELLES COMBINAISONS POUR LE TRAITEMENT DU PALUDISME

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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Priority:

06.07.2010 EP 10168641

(43)	Date of publication of application:
	15.05.2013 Bulletin 2013/20

(73)	Proprietor: BioAgency AG
	20354 Hamburg (DE)

(72)	Inventors:
	HUTCHINSON, David Kent TN16 2DR (GB) GUTTERIDGE, Winston Kent TN13 1QD (GB)

(74)	Representative: Simandi, Claus
	Badehausallee 55 27476 Cuxhaven 27476 Cuxhaven (DE)

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References cited: :

EP-B1- 1 305 031
JP-A- 2001 081 034

WO-A1-2010/004573

YOKOTA Y ET AL: "IN VITRO SYNERGISM OF FR-31564, A NEW PHOSPHONIC ACID ANTIBIOTIC", JOURNAL OF ANTIBIOTICS, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION, TOKYO, JP, vol. 34, no. 7, 1 July 1981 (1981-07-01), pages 876-883, XP000867644, ISSN: 0021-8820
SNYDER ET AL: "In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models", EXPERIMENTAL PARASITOLOGY, NEW YORK, NY, US, vol. 115, no. 3, 2 December 2006 (2006-12-02), pages 296-300, XP005724230, ISSN: 0014-4894, DOI: DOI:10.1016/J.EXPPARA.2006.09.016
BERENBAUM M C: "A method for testing for synergy with any number of agents", JOURNAL OF INFECTIOUS DISEASES, UNIVERSITY OF CHICAGO PRESS, CHICAGO, IL, vol. 137, no. 2, 1 January 1978 (1978-01-01), pages 122-130, XP008082150, ISSN: 0022-1899 cited in the application
ARAV-BOGER RAVIT ET AL: "Molecular mechanisms of resistance in antimalarial chemotherapy: the unmet challenge.", ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 2005 LNKD- PUBMED:15822189, vol. 45, 2005, pages 565-585, XP002610469, ISSN: 0362-1642


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

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