(19)
(11) EP 2 593 456 A1

(12)

(43) Date of publication:
22.05.2013 Bulletin 2013/21

(21) Application number: 11807523.3

(22) Date of filing: 14.07.2011
(51) International Patent Classification (IPC): 
C07D 487/00(2006.01)
(86) International application number:
PCT/US2011/044038
(87) International publication number:
WO 2012/009553 (19.01.2012 Gazette 2012/03)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 16.07.2010 US 365098 P

(71) Applicant: The Trustees of Columbia University in the City of New York
New York, New York 10027 (US)

(72) Inventors:
  • WASMUTH, Andrew
    Brooklyn NY 11209 (US)
  • LANDRY, Donald, W.
    New York NY 10027 (US)
  • DENG, Shi, Xian
    White Plains NY 10605 (US)
  • RAMASAMY, Ravichandran
    Ardsley NY 10502 (US)
  • SCHMIDT, Ann Marie
    Franklin Lakes NJ 07417 (US)
  • MYLARI, Banavara, L.
    East Lyme CT 06333 (US)

(74) Representative: Lawrence, John 
Barker Brettell LLP 100 Hagley Road
Edgbaston Birmingham B16 8QQ
Edgbaston Birmingham B16 8QQ (GB)

   


(54) ALDOSE REDUCTASE INHIBITORS AND USES THEREOF