(19)
(11) EP 2 606 050 A2

(12)

(88) Date of publication A3:
31.01.2013

(43) Date of publication:
26.06.2013 Bulletin 2013/26

(21) Application number: 11744008.1

(22) Date of filing: 12.08.2011
(51) International Patent Classification (IPC): 
C07D 487/04(2006.01)
A61P 35/00(2006.01)
 A61K 31/505(2006.01)
A61P 37/00(2006.01)
(86) International application number:
PCT/EP2011/063905
(87) International publication number:
WO 2012/022681 (23.02.2012 Gazette 2012/08)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 18.04.2011 US 201161476398 P
19.10.2010 WO PCT/EP2010/065700
20.08.2010 US 375358 P

(71) Applicant: Cellzome Limited
Little Chesterford Cambridgeshire CB10 1XL (GB)

(72) Inventors:
  • BELL, Kathryn
    London E8 3LT (GB)
  • PITON, Nelly
    Suffolk CB8 0GT (GB)
  • DAGOSTIN, Claudio
    Cambridge UK CB1 9YY (GB)
  • BOUSSARD, Cyrille
    Essex CB10 2AP (GB)
  • RATCLIFFE, Andrew
    Essex CM15 0QY (GB)
  • RAMSDEN, Nigel
    Herts SG8 7QP (GB)

(74) Representative: Hillier, Mark et al
GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road
Brentford, Middlesex TW8 9GS
Brentford, Middlesex TW8 9GS (GB)

   


(54) HETEROCYCLYL PYRAZOLOPYRIMIDINE ANALOGUES AS SELECTIVE JAK INHIBITORS