(19)

(11)

EP 2 606 143 A1

(12)

(43) Date of publication: 26.06.2013 Bulletin 2013/26 (21) Application number: 11752008.0 (22) Date of filing: 17.08.2011

(51) International Patent Classification (IPC):  C12P 23/00(2006.01) C12P 7/64(2006.01) C12M 1/00(2006.01) C12P 39/00(2006.01) (86) International application number: PCT/US2011/048093 (87) International publication number: WO 2012/024406 (23.02.2012 Gazette 2012/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 25.03.2011 US 201161467608 P 17.08.2010 US 858338 (71) Applicant: Battelle Memorial Institute Richland, Washington 99352 (US)	(72) Inventors: BELIAEV, Alex, S. Richland, Washington 99352 (US) PINCHUK, Grigoriy, E. Richland, Washington 99354 (US) HILL, Eric Kennewick, Washington 99336 (US) KUCEK, Leo, A. Prosser, Washington 99350 (US) (74) Representative: Brown, Fraser Gregory James  Cleveland 10 Fetter Lane London EC4A 1BR London EC4A 1BR (GB)