(19)

(11)

EP 2 609 089 A1

(12)

(43) Date of publication: 03.07.2013 Bulletin 2013/27 (21) Application number: 11748434.5 (22) Date of filing: 29.08.2011

(51) International Patent Classification (IPC):  C07D 277/24(2006.01) C07D 333/22(2006.01) A61K 31/381(2006.01) A61K 31/428(2006.01) C07D 285/14(2006.01) C07D 409/04(2006.01) A61K 31/426(2006.01) A61P 5/24(2006.01) (86) International application number: PCT/EP2011/064842 (87) International publication number: WO 2012/025638 (01.03.2012 Gazette 2012/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 15.03.2011 EP 11158310 27.08.2010 EP 10174408 (71) Applicants: Universität des Saarlandes 66123 Saarbrücken (DE) Elexopharm GmbH 66123 Saarbrücken (DE)	(72) Inventors: HARTMANN, Rolf 66111 Saarbrücken (DE) FROTSCHER, Martin 66280 Sulzbach (DE) MARCHAIS-OBERWINKLER, Sandrine 66440 Blieskastel (DE) OSTER, Alexander 66111 Saarbrücken (DE) SPADARO, Alessandro 66123 Saarbrücken (DE) (74) Representative: von Kreisler Selting Werner  Deichmannhaus am Dom Bahnhofsvorplatz 1 50667 Köln 50667 Köln (DE)