INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE

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EP 2 616 442 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	17.10.2018 Bulletin 2018/42

(45)	Mention of the grant of the patent:
	08.08.2018 Bulletin 2018/32

(21)	Application number: 11779004.8

(22)	Date of filing: 14.09.2011

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International Patent Classification (IPC):

C07D 215/06^(2006.01)
C07D 401/14^(2006.01)
C07D 413/14^(2006.01)
C07D 495/04^(2006.01)
A61K 31/52^(2006.01)
A61K 31/47^(2006.01)
A61K 31/551^(2006.01)

C07D 241/44^(2006.01)
C07D 405/12^(2006.01)
C07D 473/34^(2006.01)
A61P 35/00^(2006.01)
A61K 31/4709^(2006.01)
A61K 31/497^(2006.01)
A61K 31/5377^(2006.01)

(86)	International application number:
	PCT/US2011/051531

(87)	International publication number:
	WO 2012/037204 (22.03.2012 Gazette 2012/12)

(54)	INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE PI3K-DELTA-INHIBITOREN SOWIE VERFAHREN ZU IHRER VERWENDUNG UND HERSTELLUNG INHIBITEURS DE PI3K-DELTA ET LEURS PROCÉDÉS D'UTILISATION ET FABRICATION

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME

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Priority:

14.09.2010 US 382873 P

(43)	Date of publication of application:
	24.07.2013 Bulletin 2013/30

(73)	Proprietor: Exelixis, Inc.
	Alameda, CA 94502-3010 (US)

(72)	Inventor:
	LEAHY, James, William San Leandro CA 94577 (US)

(74)	Representative: Murgitroyd & Company
	Scotland House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)

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References cited: :

WO-A1-2007/088999
WO-A1-2008/118468
WO-A1-2010/092340
WO-A2-2008/118454
WO-A2-2010/065923

WO-A1-2008/118455
WO-A1-2010/036380
WO-A1-2011/058112
WO-A2-2009/081105

F. NAWAZ KHAN ET AL: "2-Chloro-8-methyl-3-[(pyrimidin-4-yloxy)m ethyl]quinoline", ACTA CRYSTALLOGRAPHICA SECTION E STRUCTURE REPORTS ONLINE, vol. 66, no. 5, 2 April 2010 (2010-04-02), pages O1010-O1010, XP55014590, DOI: 10.1107/S1600536810011694

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).