(19)

(11)

EP 2 616 481 A2

(12)

(88) Date of publication A3: 02.08.2012 (43) Date of publication: 24.07.2013 Bulletin 2013/30 (21) Application number: 11825655.1 (22) Date of filing: 29.08.2011

(51) International Patent Classification (IPC):  C07K 14/21(2006.01) C12P 7/22(2006.01) C12N 15/63(2006.01) C12N 15/54(2006.01) C12P 1/04(2006.01) C12R 1/38(2006.01) (86) International application number: PCT/US2011/049619 (87) International publication number: WO 2012/036884 (22.03.2012 Gazette 2012/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 25.10.2010 US 455709 P 15.09.2010 US 403400 P (71) Applicant: Aligna Technologies, Inc. Hayward, CA 94545 (US)	(72) Inventors: CHATTERJEE, Ranjini Belmont, CA 94002 (US) ZAHN, Kenneth Visalia, CA 93291 (US) MITCHELL, Kenneth San Jose, CA 95110 (US) LIU, Gary, Y. Castro Valley, CA 94546 (US) (74) Representative: Moore, Michael Richard et al Keltie LLP Fleet Place House 2 Fleet Place London EC4M 7ET London EC4M 7ET (GB)