(19)

(11)

EP 2 616 549 A1

(12)

(43) Date of publication: 24.07.2013 Bulletin 2013/30 (21) Application number: 11825711.2 (22) Date of filing: 09.09.2011

(51) International Patent Classification (IPC):  C12P 19/34(2006.01) C07H 21/04(2006.01) C07H 21/02(2006.01) (86) International application number: PCT/US2011/050903 (87) International publication number: WO 2012/036972 (22.03.2012 Gazette 2012/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 17.09.2010 US 383779 P (71) Applicant: Merck Sharp & Dohme Corp. Rahway, NJ 07065-0907 (US)	(72) Inventor: ZEWGE, Daniel Rahway New Jersey 07065-0907 (US) (74) Representative: Hussain, Deeba et al Merck & Co., Inc. Patent Department MSD European Patent Department Hoddesdon, Hertfordshire EN11 9BU Hoddesdon, Hertfordshire EN11 9BU (GB)