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(11)

EP 2 619 195 A1

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(43) Date of publication: 31.07.2013 Bulletin 2013/31 (21) Application number: 10761101.4 (22) Date of filing: 24.09.2010

(51) International Patent Classification (IPC):  C07D 403/14(2006.01) A61K 31/4178(2006.01) (86) International application number: PCT/US2010/050138 (87) International publication number: WO 2012/039717 (29.03.2012 Gazette 2012/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (71) Applicant: Bristol-Myers Squibb Company Princeton, NJ 05843-4000 (US)	(72) Inventors: BELEMA, Makonen Wallingford, CT 06492 (US) HEWAWASAM, Piyasena Wallingford Connecticut 06492 (US) (74) Representative: Reitstötter - Kinzebach  Patentanwälte Sternwartstrasse 4 81679 München 81679 München (DE)