| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
|
Designated Extension States: |
|
BA ME |
| (30) |
Priority: |
17.05.2011 US 201161486814 P 29.03.2011 US 201161468607 P 31.01.2011 US 201161437696 P 27.09.2010 US 386619 P 27.09.2010 EP 10180485
|
| (43) |
Date of publication of application: |
|
07.08.2013 Bulletin 2013/32 |
| (73) |
Proprietor: MorphoSys AG |
|
82152 Martinsried/Planegg (DE) |
|
| (72) |
Inventors: |
|
- ROJKJAER, Lisa
8908 Hedingen (CH)
- BOXHAMMER, Rainer
85653 Aying (DE)
- ENDELL, Jan
80333 München (DE)
- WINDERLICH, Mark
81371 München (DE)
- SAMUELSSON, Christofer
83607 Holzkirchen (DE)
|
| (74) |
Representative: Hutter, Bernd et al |
|
MorphoSys AG
Lena-Christ-Straße 48 82152 Martinsried/Planegg 82152 Martinsried/Planegg (DE) |
| (56) |
References cited: :
WO-A2-2007/042309
|
WO-A2-2008/037257
|
|
| |
|
|
- WIERNIK PETER H: "Treatment of hematologic neoplasms with new immunomodulatory drugs
(IMiDs).", CURRENT TREATMENT OPTIONS IN ONCOLOGY APR 2009 LNKD- PUBMED:19016330, vol.
10, no. 1-2, April 2009 (2009-04), pages 1-15, XP009145844, ISSN: 1534-6277
- STEVENSON G T: "CD38 as a therapeutic target", MOLECULAR MEDICINE 200611 US LNKD-
DOI:10.2119/2006-00082.STEVENSON, vol. 12, no. 11-12, November 2006 (2006-11), pages
345-346, XP009145827, ISSN: 1076-1551
- RICHARDS TIFFANY ET AL: "Advances in treatment for relapses and refractory multiple
myeloma", MEDICAL ONCOLOGY (TOTOWA), vol. 27, no. Suppl. 1, June 2010 (2010-06) ,
pages 25-42, XP009145832, ISSN: 1357-0560
- LAPALOMBELLA ROSA ET AL: "Lenalidomide down-regulates the CD20 antigen and antagonizes
direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic
lymphocytic leukemia cells", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 112,
no. 13, 15 December 2008 (2008-12-15), pages 5180-5189, XP009145765, ISSN: 0006-4971
- GHOSH NILANJAN ET AL: "Bortezomib and Thalidomide, a Steroid Free Regimen in Newly
Diagnosed Patients with Multiple Myeloma", BLOOD, vol. 114, no. 22, November 2009
(2009-11), page 1119, XP009145845, & 51ST ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY;
NEW ORLEANS, LA, USA; DECEMBER 05 -08, 2009
- VAN DER VEER MICHAEL S ET AL: "Towards effective immunotherapy of myeloma: enhanced
elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal
antibody daratumumab.", HAEMATOLOGICA FEB 2011 LNKD- PUBMED:21109694, vol. 96, no.
2, February 2011 (2011-02), pages 284-290, XP009145823, ISSN: 1592-8721
|
|