Urine and serum biomarkers associated with diabetic nephropathy

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EP 2 623 517 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	30.12.2015 Bulletin 2015/53

(45)	Mention of the grant of the patent:
	16.09.2015 Bulletin 2015/38

(21)	Application number: 13162626.9

(22)	Date of filing: 27.01.2010

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International Patent Classification (IPC):

C07K 16/38^(2006.01)
C40B 30/00^(2006.01)
G01N 33/573^(2006.01)
C07K 14/81^(2006.01)

C07K 16/18^(2006.01)
G01N 33/53^(2006.01)
G01N 33/68^(2006.01)
C07K 14/47^(2006.01)

(54)	Urine and serum biomarkers associated with diabetic nephropathy Mit diabetischer Nephropathie assoziierte Urin-und Serumbiomarker Biomarqueurs urinaires et sériques associés à une néphropathie diabétique

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

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Priority:

28.01.2009 US 147778 P

(43)	Date of publication of application:
	07.08.2013 Bulletin 2013/32

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	10735454.0 / 2391654

(73)	Proprietor: Industrial Technology Research Institute
	Hsinchu, 31040 Taiwan (TW)

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Inventors:

Lin, Wei-Ya
Dali City Taiwan 412 (TW)
Yeh, Mary Ya-Ping
Taipei City Taiwan 105 (TW)
Tseng, Tzu-Ling
Chiayi City Taiwan 600 (TW)
Cheng, Ping-Fu
Xizhou Township Taiwan 524 (TW)
Hsu, Tsai-Wei
Taoyuan City Taiwan 330 (TW)
Li, Hung-Yi
Xinying City Taiwan 730 (TW)
Chen, Yi-Ting
Longtan Township Taiwan 325 (TW)
Lin, Yuh-Feng
Taipei City Taiwan 116 (TW)
Chen, Giien-Shuen
Taipei City Taiwan 100 (TW)
Li, Yen-Peng
Taipei City Taiwan 106 (TW)

(74)	Representative: Fuchs Patentanwälte Partnerschaft mbB
	Patentanwälte Westhafenplatz 1 60327 Frankfurt am Main 60327 Frankfurt am Main (DE)

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References cited: :

EP-A1- 1 760 088
WO-A1-2010/031822
US-A1- 2006 286 602

WO-A1-03/019193
WO-A2-2007/051069

RAO PATURI V ET AL: "Proteomic identification of urinary biomarkers of diabetic nephropathy", DIABETES CARE, AMERICAN DIABETES ASSOCIATION, ALEXANDRIA, VA, US, vol. 30, no. 3, 1 March 2007 (2007-03-01), pages 629-637, XP002492989, ISSN: 0149-5992, DOI: 10.2337/DC06-2056
VARGHESE SANJU A ET AL: "Urine biomarkers predict the cause of glomerular disease", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, WILLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 18, no. 3, 1 March 2007 (2007-03-01), pages 913-922, XP002492993, ISSN: 1046-6673, DOI: 10.1681/ASN.2006070767
HIROSHI YAMAGUCHI ET AL: "Progression of Diabetic Nephropathy Enhances the Plasma Osteopontin Level in Type 2 Diabetic Patients", ENDOCRINE JOURNAL, vol. 51, no. 5, 1 January 2004 (2004-01-01), pages 499-504, XP055068414, ISSN: 0918-8959, DOI: 10.1507/endocrj.51.499
JAIN S ET AL: "PROTEOMIC ANALYSIS OF URINARY PROTEIN MARKERS FOR ACCURATE PREDICTION OF DIABETIC KIDNEY DISORDER", JOURNAL OF ASSOCIATION OF PHYSICIANS OF INDIA, ASSOCIATION OF PHYSICIANS OF INDIA, BOMBAY, IN, vol. 53, 1 June 2005 (2005-06-01), pages 513-520, XP008068535, ISSN: 0004-5772


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).