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EP 2 625 178 A1

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(43) Date of publication: 14.08.2013 Bulletin 2013/33 (21) Application number: 11830125.8 (22) Date of filing: 07.10.2011

(51) International Patent Classification (IPC):  C07D 417/14(2006.01) C07D 403/14(2006.01) A61P 31/04(2006.01) C07D 471/04(2006.01) A61K 31/429(2006.01) A61K 31/428(2006.01) C07D 413/14(2006.01) (86) International application number: PCT/AU2011/001284 (87) International publication number: WO 2012/045124 (12.04.2012 Gazette 2012/15)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 08.10.2010 US 391163 P (71) Applicant: Biota Europe Ltd Yarnton Oxfordshire OX5 1PF (GB)

(72) Inventors: PALMER, James T Victoria 3168 (AU) LUNNISS, Christopher James Victoria 3168 (AU) OFFERMANN, Daniel A Victoria 3168 (AU) AXFORD, Lorraine Claire Victoria 3168 (AU) BLAIR, Michael Victoria 3168 (AU) MITCHELL, Dale Robert Walden Essex CB10 1XL (GB) PALMER, Nicholas John Walden Essex CB10 1XL (GB) STEELE, Christopher Walden Essex CB10 1XL (GB) ATHERALL, John Walden Essex CB10 1XL (GB) WATSON, David Walden Essex CB10 1XL (GB) HAYDON, David John Yarnton Oxfordshire OX5 1PF (GB) CZAPLEWSKI, Lloyd George Yarnton Oxfordshire OX5 1PF (GB) DAVIES, David Yarnton Oxfordshire OX5 1PF (GB) COLLINS, Ian Yarnton Oxfordshire OX5 1PF (GB) TYNDALL, Edward Malcolm Victoria 3168 (AU) ANDRAU, Laura Victoria 3168 (AU) PITT, Gary Robert William Victoria 3168 (AU) (74) Representative: Smyth, Gyles Darren  EIP Fairfax House 15 Fulwood Place London WC1V 6HU London WC1V 6HU (GB)